By Stacey L. McDonald
This thesis studies the newest advancements within the direct amination of assorted C−H bonds utilizing an H−Zn exchange/electrophilic amination strategy. McDonald and colleagues display this method of be a fast and strong technique for having access to a number of functionalized amines.
The fabric defined during this e-book indicates how McDonald completed C−H zincation utilizing robust, non-nucleophilic zinc bases and next electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines because the electrophilic nitrogen resource.
McDonald’s findings are of relevance to medicinal chemistry, drug discovery and fabrics technological know-how. Her thesis is a resource of proposal for scientists getting into the sector and scholars starting their PhD in a similar area.
Read Online or Download Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C−H Bonds (Springer Theses) PDF
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This thesis studies the most recent advancements within the direct amination of varied C−H bonds utilizing an H−Zn exchange/electrophilic amination strategy. McDonald and colleagues exhibit this method of be a swift and strong technique for having access to various functionalized amines. the cloth defined during this booklet exhibits how McDonald accomplished C−H zincation utilizing powerful, non-nucleophilic zinc bases and next electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines because the electrophilic nitrogen resource.
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Extra info for Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C−H Bonds (Springer Theses)
Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C−H Bonds (Springer Theses) by Stacey L. McDonald